Bisphosphonates (Actonel, Boniva, Fosamax, Reclast, Skelid, Zometa, Aredia) (January 7, 2008)

FDA issued a warning of the possibility of severe and sometimes incapacitating bone, joint, and/or muscle pain in patients taking bisphosphonates. This pain may occur within days, months, or years after starting a bisphosphonate. Healthcare professionals should consier the association between musculoskeletal pain and bisphosphonates in any patient currently taking a bisphonsphonate who presents with such symptoms.